Abstract
THE nature of the relationship between the X and Y chromosome in human spermatocytes has not been clearly explained by the extensive cytological studies of the last 50 yr (see refs 1–3 for reviews). The sex chromosomes of man and other mammals form a condensed mass (the so-called ‘sex vesicle’) during zygotene–pachytene in spermatocyte nuclei. Because of its density, the internal structure of the sex vesicle could not previously be studied by light microscopy. We describe here a technique which clearly stains the sex chromosomes within the condensed sex vesicle.
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