Abstract
Abstract Sequential treatment of S-methyl (t-butyl)phenyl- or (1-naphthyl)phenylphosphinothioates with lithium dialkylamides at −78 °C and then with alkyl halides at 0 °C—r.t. gave the corresponding (alkylthiomethyl)phosphine oxides, the Wittig rearrangement products, in moderate to good yields along with small amount of their overreacted α-alkylated products. The corresponding alkylphosphine oxide was obtained only in the reaction of naphthyl derivative. Optically active Wittig rearrangement products were given in 82 and 78% optical yields, respectively.
Published Version
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