Abstract
ABSTRACT.The intracarotid amobarbital procedure (IAP), or Wada test, was initially performed to ascertain hemispheric language dominance during cranial surgery. It was later used to help test memory and define the focus of epileptogenic tissue, especially in patients being evaluated for temporal lobe resection. Although there are hints the IAP may be displaced by functional PET or fast MRI, it remains a very useful tool for mapping cognitive functions before surgery and for research.This article discusses the Wada test in general; its duration of effects upon various brain structures; and its use for testing language dominance, memory, and localization of foci. The effect of the Wada test on EEG is reviewed, including how slow wave (delta) activity may be used to estimate the drug's duration and effect on brain functions. The protocol from a neurosurgery center is also examined, as a suggested model for standardization.
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