Abstract
Juxta-articular myxoma is an uncommon, benign, hypocellular, bland, myxoid neoplasm of mesenchymal origin occurring within the vicinity of a large joint such as the knee. The neoplasm is exemplified within 16 years to 83 years with a median age at 43 years. A male predominance is observed with a male to a female proportion of nearly 3:1. Localized tissue destruction arising on account of the neoplasm can engender pain or nerve palsy. The minimally cellular tumefaction depicts an abundant, myxoid stroma admixed with a non-malignant proliferation of spindle-shaped cells. Juxta-articular myxoma is immune reactive to vimentin and CD34.
Highlights
Juxta-articular myxoma is an uncommon, benign, hypocellular, hypo-vascular, bland, myxoid neoplasm of mesenchymal origin emerging within the vicinity of a large joint
Juxta-articular myxoma is an uncommon, benign, hypocellular, bland, myxoid neoplasm of mesenchymal origin occurring within the vicinity of a large joint such as the knee
Disease Characteristics Juxta-articular myxoma is commonly associated with large joints such as the knee which is incriminated in a majority (88%) of instances
Summary
Juxta-articular myxoma is an uncommon, benign, hypocellular, hypo-vascular, bland, myxoid neoplasm of mesenchymal origin emerging within the vicinity of a large joint. Disease Characteristics Juxta-articular myxoma is commonly associated with large joints such as the knee which is incriminated in a majority (88%) of instances. Hypocellular and hypo-vascular tumefaction composed of miniature, stellate or spindle-shaped cells admixed within an abundant myxoid matrix is observed [3,4]. The neoplasm consists of thick-walled, cystic articulations with the dissemination of miniature, elliptical to spindle-shaped and fibroblast-like cells embedded within an abundantly myxoid stroma. Minimal quantities of spindle-shaped, fibroblast-like, stellate or fusiform cells are entangled within a network of reticulin fibres, myxoid matrix and inadequately configured vascular articulations. Spindle-shaped cells are enveloped within a hypovascular, myxoid matrix with scattered, variable cystic articulations [3,4]. Foci of enhanced cellularity may be denominated [4,5]
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