The Verigene dilemma: gram-negative polymicrobial bloodstream infections and clinical decision making

Abstract

Verigene Blood-Culture Gram-Negative (GN) results in rapid identification of key GNs in bloodstream infections. Its use clinically is limited by low sensitivity in polymicrobial GN infections and concerns for inappropriate antibiotic modification. In a retrospective review of 1003 blood culture sets, the incidence of missed GNs was infrequent, <4%, with the potential to negatively impact the management of GN BSIs in <2% of cases.