The Variation of Neutrophil Count at Different Phases of the Menstrual Cycle in Periodontally Healthy Females

Abstract

Introduction: The effect of different levels of sex hormones in the body is to bring out changes in every part of the body. The changes occurring in periodontium under the influence of female sex hormones during menstrual cycle is important from the perspective of periodontal health. Aim: The purpose of this study is to compare the neutrophil count at different time points during menstrual cycle in GCF and to compare the neutrophil count with clinical parameters. Materials and Method: Fifty five periodontally healthy women with regular menstrual cycle were included in the study. Clinical parameters recorded were Gingival bleeding index (GBI) and the Modified Gingival index (MGI) at each phase of menstrual cycle(Ovulatory phase OP, Menstrual phase MH and Premenstruation phase PMP). Gingival crevicular fluid (GCF) was collected at each study phase for analysis ofneutrophil count. Results: Both the GBI and the MGI increased remarkably during the menstrual cycle, and were significantly higher during ovulation than in menstruation and premenstruation phase. The level of neutrophils increased during the different phases of menstrual cycle, highest count being observed during the ovulatory phase. Conclusion: It was concluded that periodontal health is altered during different phases of menstrual cycle.