Abstract
背景与目的国内外目前已有多篇现场细胞学应用于经支气管镜针吸活检（transbronchial needle aspiration, TBNA）的报道，但专门针对肺癌患者的研究很少。本研究的目的是探讨TBNA联合现场细胞学在肺癌诊断中的作用。方法回顾性分析2012年12月-2013年12月在滨州市人民医院行TBNA并最终确诊为肺癌的69例患者，其中行现场细胞学者37例，未行现场细胞学者32例。比较现场细胞学结果与最终HE染色结果的一致性，同时比较两组患者的诊断率、每个淋巴结穿刺针数、并发症发生率及细胞学诊断费用。结果现场细胞学与HE染色一致性为94.1%（32/34）。现场细胞学组诊断率与非现场细胞学组相比无统计学差异（91.9% vs 78.1%, P=0.20）；但平均穿刺针数及并发症发生率，现场细胞学组少于非现场细胞学组（t=29.5, P < 0.05; χ2=4.4, P < 0.05），现场细胞学组患者细胞学诊断费用低于非现场细胞学组（t=10.9, P < 0.05）。结论TBNA联合现场细胞学诊断肺癌，与HE染色一致性好，且能减少穿刺针数及并发症，节省细胞学诊断费用，值得推广。
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