Abstract
Advances in antiretroviral therapy for both Human Immunodeficiency Virus (HIV) treatment and prevention have increased interest in adherence to HIV treatment. This is because the individual patient and public health benefits of antiretroviral treatment (ART) greatly depend on the extent to which people living with HIV (PLHIV) adhere to the prescribed daily dosing regimens. Studies have shown that nonadherence to ART increases drug resistance, morbidity and person-to-person HIV transmission. Public health experts are trying different innovations to enhance ART adherence, including promoting support groups of PLHIV. The purpose of this study was to determine the value of support group participation in enhancing ART adherence. The study used a cross-sectional design to compare ART adherence among PLHIV who participate in support group activities and those who do not. Respondents were adults who were initiated on ART between January 1, 2010 and December 31, 2012. Multistage probability sampling was used to select study sites and respondents. Data was collected using a self-administered questionnaire from 1676 respondents between February and May 2014. Data was analyzed using STATA. Univariate analysis was carried out to generate descriptive statistics, while Chi-square tests were used to examine if there was an association between participation in support group activities and antiretroviral treatment adherence. ART adherence was self-reported by 745/788 (95%) and 814/888 (92%) respondents who had ever and had never participated in support group activities respectively. Among respondents who reported nonadherence to ART, 74/117 (8%) had never participated in support group activities compared to just 43/117 (5%) who participated in support group activities. These findings suggest that PLHIV who participate in support group activities are more likely to adhere to ART than those who do not participate. This implies that there is value in participating in support groups by PLHIV in terms of ART adherence.
Highlights
Success in antiretroviral treatment (ART) for both Human Immunodeficiency Virus (HIV) treatment and prevention has rekindled interest in interventions that enhance ART adherence. This is because the public health impact of ART in reducing HIV transmission and enhancing treatment outcomes greatly depend on the extent to which people living with HIV (PLHIV) adhere to the prescribed daily dosing regimens of antiretroviral medicines
The purpose of this study was to determine the value of participation in PLHIV support groups in ART adherence
A total of 1676 PLHIV participated in this study
Summary
Success in antiretroviral treatment (ART) for both Human Immunodeficiency Virus (HIV) treatment and prevention has rekindled interest in interventions that enhance ART adherence. This is because the public health impact of ART in reducing HIV transmission and enhancing treatment outcomes greatly depend on the extent to which people living with HIV (PLHIV) adhere to the prescribed daily dosing regimens of antiretroviral medicines. Researchers have identified multiple factors associated with nonadherence to ART These fall into broad categories including psychosocial issues, economic factors, substance abuse, co-morbidities including psychiatric disease, low health literacy, and medication-related issues. Many of these factors are modifiable with adherence enhancing interventions [3]
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