Abstract
ObjectivesRadical nephrectomy (RN) was the standard treatment for renal cell carcinoma (RCC). However, recent studies have found that partial nephrectomy (PN) could achieve similar effects as radical nephrectomy, and has the advantages of less bleeding and shorter hospital stay. The choice of surgical strategies has become a concern of clinicians, which could be guided by renal score introduced by Kutikov et al Therefore, we conducted this meta‐analysis to clarify the value of renal score of determining surgical strategies and predicting complications.MethodsThe keywords “RENAL score,” “renal nephrometry score,” or “nephrometry score” were used to retrieve electronic databases for relevant literature up to Feb 2020, including PubMed, Web of Science, and the Cochrane library. Surgical strategies and complications are outcome measures. Risk ratio (RR) with 95% confidence intervals (CI) is applied to assess the effect size.ResultsA total of 20 studies met the selection criteria for meta‐analysis. There was significant difference in RN operation rate for each subgroup (low‐moderate: RR = 3.50, 95% Cl = 2.60‐4.71, P < .001; low‐high: RR = 6.29, 95% Cl = 4.40‐9.00, P < .001; moderate‐high: RR = 1.80, 95% Cl = 1.39‐2.32, P < .001).The overall incidence of complications from high renal score group was significantly higher than that in low renal score group (low‐moderate: RR = 1.32, 95% Cl = 1.03‐1.69, P = .026; low‐high: RR = 2.45, 95% Cl = 1.48‐4.07, P = .001; moderate‐high: RR = 1.75, 95% Cl = 1.17‐2.61, P = .007).ConclusionsThis meta‐analysis indicated that renal score is an efficient tool for determining surgical strategies and predicting complications in PN. More prospective research is essential to verify the predictive value of renal score.
Highlights
Renal cell carcinoma (RCC) is the sixth most commonly diagnosed cancer in men and the tenth most commonly diagnosed cancer in women, accounting for 5% and 3% of all tumors respectively.[1]
In order to select appropriate surgical strategies and better predict complications, several renal cancer scoring systems for describing the relevant renal mass anatomy have emerged as the times require
The results showed that the effect of renal score on complications is not disturbed by surgical techniques (Table 3)
Summary
Renal cell carcinoma (RCC) is the sixth most commonly diagnosed cancer in men and the tenth most commonly diagnosed cancer in women, accounting for 5% and 3% of all tumors respectively.[1]. In order to select appropriate surgical strategies and better predict complications, several renal cancer scoring systems for describing the relevant renal mass anatomy have emerged as the times require
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