Abstract
The 63 infants with perinatal infections were surveyed for assesment the diagnostic and prognostic values of following indicators neuron specific enolase, interleukin 1β (IL-1β), interleukin-6 (IL-6). The level of NSE was 2.5 times, with mixed infection was 4 times higher in newborns with CMV infection and bacterial infection than the control infants. The reliably high levels of cytokines, namely IL-6, IL-1β were observed in mixed association of pathogens and in infants with bacterial infection compared with mono-CMV infection. Above mentioned result was revealed while comparing the levels of cytokines in newborn infants depending on the etiology. So that, neuro immunological parameters of blood serum can be used as criteria for early diagnosis and prediction of cerebral lesions in newborns with perinatal infections.
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