Abstract
Objective: To investigate the application of liquid chromatography-mass spectrometry (LC-MS) in the determination of chemical constituents of kidney tonic and aphrodisiac Chinese herbal preparations. Methods: In this study, 30 kidney tonic and aphrodisiac Chinese herbal preparations were selected as experimental materials, and chromatography and LC-MS were used to detect their chemical compositions in the control group and the experimental group, respectively. The excellent rate of detection method, identification time, and accuracy of the two methods were compared. Results: The excellent rate of the detection method in the experimental group (93.33%) was significantly higher than that in the control group (73.33%), and the difference was statistically significant (P < 0.05); compared with the control group, the detection time and retention time error in the experimental group were shorter, and the difference showed highly significant correlation (P < 0.001). Conclusion: LC-MS is of high value in the detection of chemical constituents of kidney tonic and aphrodisiac Chinese herbal preparations, which can significantly improve the excellent rate of the detection method and the success rate, shorten the detection time, and reduce the retention time error, and is worth to be popularized.
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