The value of intraoperative facial nerve electromyography in predicting facial nerve function after vestibular schwannoma surgery

Abstract

The prognostic significance of intraoperative facial nerve electromyography (EMG) changes is not well-established in vestibular schwannoma (VS) surgery. We studied facial nerve EMG with a threshold >0.05 mA and performed subgroup analyses based on tumor size, resection approach, and extent of resection, for prediction of long-term facial nerve outcome. A total of 477 surgically treated VS patients were included. Elevated stimulation threshold exceeding >0.05 mA is a highly specific (90%), but very insensitive (29%) finding in this cohort. The positive predictive value and negative predictive values (NPV) of facial nerve EMG for detection of permanent facial palsy are 68% and 63%, respectively. The NPV decreased with increasing tumor size (72% versus [ vs.] 64% vs. 53%) due to the increasing prevalence of post-operative facial nerve palsy in these patients. In conclusion, while facial nerve EMG is a critical adjunct for locating the facial nerve intraoperatively, its predictive value for facial nerve function remains to be determined.