The value of I-SCAN technology for diagnosis of colorectal polyps

Abstract

Objective To investigate the value of I-SCAN technology for diagnosis of colorectal polyps by comparing the difference of detection rate in polyp and adenoma between I-SCAN and normal high-definition endoscopy groups. Methods This study was a single-center, prospective, randomized case controlled study. The patients of two groups were allocated at random using the table of random numbers. The intubation procedures in experimental group were under normal high-definition mode while the withdrawal procedures were under I-SCAN mode. In the controlled group, all the procedures were under normal high-definition mode.The photographing and biopsy operation was done only in withdrawal procedures. All the lesions were diagnosed by pathology. The polyp detection rate and adenoma detection rate were evaluated. Results A total of 228 patients were included in the study, 115 patients in experimental group while 113 in controlled group. There was no significant difference in withdraw time [(7.3±3.6)min VS (6.4±4.3)min, P=0.07] and the colon cleanliness[(7.4±1.5) VS (7.4±2.3), P=0.942] between the experimental group and the controlled group. And there was no complication in either group. The detection rate of colorectal polyps of the experimental group was 57.39% (66/115), while that of controlled group was 33.62%(38/113), with significant statistical difference(P=0.001). The detection rate of colorectal adenoma of the experimental group was 35.65% (41/115), while that of the controlled group was 24.78% (28/113), with no significant difference(P=0.074). Conclusion The polyp detection rate of I-SCAN group is higher than normal high-definition endoscopy group. I-SCAN has broad prospects. Key words: Colorectal neoplasms; Colorectal polyps; Colorectal adenoma; I-SCAN; Detection rate