The value of hemoglobin A(1c) in type 2 diabetic patients with infected foot

Abstract

Objective To evaluate the value of HbA 1 c in type 2 diabetic patients with infected foot.Methods 159 type 2 diabetic patients with infected foot ulcers (Wagner' s grade 1-5) were retrospectively enrolled and divided into diabetic foot infection group (n=75) and no diabetic foot infection group (n=84),recording demographic characteristics.Results 159 type 2 diabetic patients with infected foot ulcers were analyzed,male accounting for 64.2％,the average age of (68.8 ± 11.6) years old,the average duration of diabetes of (9.6 ± 7.4) years.The level of HbA 1C was (7.0 ± 3.9)％.The duration of ulcer was (19.4 ± 15.0) days and toe lesions was commoner (45.3％),28.3％-40.3％ of ulcers were Wagner staged 1 or 2.Most of patients had diabetic complications including peripheral neuropathy (52.8％),lower extremity vascular disease (30.8％),diabetic nephropathy (20.1％).A total of 91 isolates were detected.Among them,50.5％ were gram-positive cocci,the majority were Staphylococcus aureus (28.6％); 41.8％ were gram-negative bacilli,the majority were Escherichia coli (22.0％).The duration of ulcer and the level of HbAlc in DFI group were significantly higher than those in NDFI group (P ＜ 0.01).However,age and duration of diabetes in two groups showed no significant differences (P ＞ 0.01).Conclusions Diabetic foot is the result of multiple factors.It is necessary to monitor the level of HbA I c for individualized treatment. Key words: Diabetic foot; Infection; Glycosylated hemoglobin