Abstract

This research was aimed at exploring the application value of endoscopic ultrasonography (EUS) in the diagnosis of gastric cancer staging and the correlation between staging and clinical features of gastric cancer. A total of 72 patients with gastric cancer were selected and randomly divided into two groups. The patients in the pathological group underwent postoperative pathological examination, while those in the EUS group received preoperative EUS examination. The results showed that the staging accuracy of EUS was 73.33% for T1, 78.57% for T2, 27% for T3, and 100% for T4, compared with the pathological staging. The accuracy of N- and N+ was 42.5% and 82.3% in EUS, respectively, and the total accuracy was 55.7%. There was no considerable difference in the accuracy of T staging between early gastric cancer and advanced gastric cancer (P > 0.05), but there was a considerable difference in N staging (P < 0.05). Lymph node metastasis affected the accuracy of N staging (P < 0.05). The number and location of metastatic lymph nodes did not affect the judgment of metastatic lymph nodes (P > 0.05). In addition, the proportion of understaging and overstaging was greatly different among different lesion sizes and histological types of gastric cancer (P < 0.05). To sum up, the accuracy of EUS for T and N staging of gastric cancer needed to be improved. The location of gastric cancer lesions affected the accuracy of T staging, while the depth of invasion and lymph node metastasis affected the accuracy of N staging.

Highlights

  • Gastric cancer is the fifth most common malignant tumor [1]

  • A total of 72 patients with gastric cancer were selected from January 2019 to July 2021 in the hospital, who underwent endoscopic ultrasonography (EUS) examination and received surgical treatment

  • All measurement data were expressed as mean ± standard deviation (x ± S). Whether it affected the accuracy of T and N staging by EUS, chi-square test and multiple logistic regression were used to analyze it

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Summary

Introduction

Gastric cancer is the fifth most common malignant tumor [1]. Just in 2012, there were 9.52 million new cases of gastric cancer worldwide, about half of which occurred in East Asia (mainly China). Gastric cancer ranks second among malignant tumors. In China, the population-adjusted mortality rates of gastric cancer were 408/100,000 for males and 186/100,000 for females, and there were considerable differences between urban and rural areas. Patients with early gastric cancer are usually asymptomatic or have atypical symptoms, so the diagnosis of early gastric cancer is difficult. Most patients with typical symptoms have entered the advanced stage, and the prognosis is poor [2, 3]. Accurate diagnosis of gastric cancer at an early stage is conducive to improving the survival rate of gastric cancer patients [4]

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