Abstract

Background: Headache is among the most prevalent complaints in patients presenting to the emergency department (ED). Clinicians are faced with the difficult task to differentiate primary (benign) from secondary headache disorders, since no international guidelines currently exist of clinical indicators for neuroimaging in headache patients.Methods: We performed a retrospective review of 501 patients who presented at the ED with headache as a primary complaint between April 2018 and December 2018. Primary outcomes included the amount of diagnostic imaging, the different conclusions provided by diagnostic imaging, and the clinical factors associated with abnormal imaging results.Results: About half of the patients were diagnosed with a primary headache disorder. Cranial CT imaging at the ED was performed regularly (61% of the patients) and led to the diagnosis of underlying pathology in 1 in 7.6 patients. In a multivariate model, factors significantly associated with abnormal cranial CT results were age 50 years or older, presentation within 1 h after headache onset, clinical history of aphasia, and focal neurological deficit at examination.Conclusions: As separate clinical characteristics have limited value in detecting severe underlying headache disorders, cranial imaging is regularly performed in the ED. Clinical prediction model tools applied to headache patients may identify patients at risk of intracranial pathology prior to diagnostic imaging and reduce cranial imaging in the future.

Highlights

  • Headache is among the most prevalent complaints in patients presenting to the emergency department (ED)

  • Clinical clues for secondary headache causes can be obtained from vital signs and extensive neurological examination; these may be absent in a substantial amount of patients with intracranial pathology

  • We evaluated 501 patients with headache as primary complaint presenting to the ED

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Summary

Introduction

Headache is among the most prevalent complaints in patients presenting to the emergency department (ED). Clinicians are faced with the difficult task to differentiate primary (benign) from secondary headache disorders, since no international guidelines currently exist of clinical indicators for neuroimaging in headache patients. Headache is among the most common complaints in patients evaluated in the emergency department (ED), accounting for ∼2.3% of all ED visits [1,2,3]. Clinicians may experience difficulty in differentiating primary (benign) headache disorders from secondary causes requiring prompt neuroimaging in the emergency setting [4]. The majority of patients admitted to the ED with headache are diagnosed with a benign primary headache disorder. About 10% of headache patients are diagnosed with severe secondary headache disorders including trauma, hemorrhage, vascular pathology, infection, or malignancy [5,6,7].

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