The value of bronchial and cavity contraction rates in differentiating benign and malignant pulmonary cavities

Hua Zhang,Xia Qian,Zheng-Hua Liu,Yi Gong

doi:10.1186/s12890-020-01238-z

Abstract

BackgroundThe present study aimed to assess the value of bronchial and cavity contraction percentages in differentiating benign and malignant pulmonary cavities.MethodsForty-two patients with pulmonary cavities were scanned by dual-phase computed tomography (CT). Then, the cavity and bronchial contraction percentages were respectively measured, the differences between the benign and malignant cavities were compared, and the best diagnostic critical point for differentiating benign and malignant cavities was obtained through the receiver operator characteristic (ROC) curve of the diagnostic test.ResultsThe contraction percentage of the bronchial end with benign cavities was significantly higher than that of the bronchial end with malignant cavities (P < 0.001). The contraction percentage was significantly higher in the benign group than in the malignant group (P < 0.001). The ROC analysis revealed that the sensitivity and specificity of the bronchial contraction percentage was 90.50 and 86.40%, respectively, while the sensitivity and specificity of the cavity contraction percentage was 90.50 and 90.90%, respectively.ConclusionThe dual-phase CT scanning of the bronchial and cavity contraction percentage can distinguish between benign and malignant cavities.

Highlights

The present study aimed to assess the value of bronchial and cavity contraction percentages in differentiating benign and malignant pulmonary cavities
Inspection methods A Philips BRILLIANCE 64-slice spiral computed tomography (CT) machine and data post-processing workstations were used for the present study
The multiplanar or surface reconstruction of the post-processing workstation was used to display the bronchi connected with the cavities, and the diameter of the bronchial end with the cavities, the left-right inner diameters of the cavity, and the front-back inner diameter of the cavity were measured, respectively

Summary

Introduction

The present study aimed to assess the value of bronchial and cavity contraction percentages in differentiating benign and malignant pulmonary cavities. The pulmonary cavity can present with tissue necrosis, disintegration, and bronchial drainage, and mainly manifests as lung cancer, tuberculosis, and inflammatory cavities [1–3]. A benign cavity is comprised of granulation tissue, fibrous tissue, necrotic tissue, and various inflammatory cells. In addition to cancerous tissues, the trabeculae of damaged or residual bronchial cartilage and vascular connective trabecula can be found in the wall of the cancerous cavity. In order to improve the ability of imaging in differentiating benign and malignant cavities, the investigators compared the bronchial contraction percentage and cavity contraction percentage between benign and malignant cavities

Methods

Results

Discussion

Conclusion