The value of 3 T MR diffusion tensor fiber tractography study of association fasciculus of normative human in vivo primarily

Abstract

Objective To exhibit the fibers of association fascicules,aims at demonstrating the association fibers of brain with diffusion tensor fiber tracking technique.Methods Conventionality MRI, diffusion tensor imaging(DTI)and diffusion tensor fiber tractography(DT-FT)were performed in twenty healthy subjects,including eighteen right-handed(sixteen men and four women)and two left-handed(one male and one female)by 3 T Siemens Trio 2003 T MRI.To select arcuate faseicules,inferior longitudinal fascicules,frontal-occipital fascicules,corpus callosum,posterior limb of internal capsule and external capsule as seeds used to track fibers.Results Diffusion tensor fiber tracking exhibited bundles of external capsule left mean fibers were 308 bundles,right fibers were 307 bundles(t=0.138,P0.05),frontal- occipital tracks left mean fibers were 115 bundles,right fibers were 110 bundles(t=1.174,P0.05),and their fractional anisotropy(FA)valueextemal capsule mean FA left was 0.361,the fight was 0.362 (t= -0.184,P0.05).Frontal-occipital tracks mean fractional anisotropy left was 0.352,the right was 0.351(t= -0.816,P0.05).The difference between both sides were statistically insignificant(P 0.05).The posterior limb of internal capsule left mean fibers were 249 bundles,fight fibers were 257 bundles(t= -0.818,P0.05),arcuate fasciculesleft mean fibers were 198 bundles,right fibers were 204 bundles(t= -0.465,P0.05)fibers difference between both sides were statistically insignificant (P0.05),but the individual difference was significant,and their fractional anisotropy difference between both sides(posterior limb of internal capsule mean FA left was 0.450,the right was 0.444(t=2.771,P 0.01).Arcuate fascicules mean FA left was 0.386,the right was 0.375(t=1.912,P0.05)were statistically significant(P0.05).Inferior longitudinal fascicules left mean fibers were 138 bundles,right fibers were 116 bundles(t=1.739,P0.05)and fractional anisotropy difference between both sides mean FA left was 0.377,the right was 0.359(t=2.606,P0.01)were statistically significant(P0.05). There may be a new association fascicules inner 4 brain lobes,the fascicules in the same side hemisphere, associated with the frontal,temporal,parietal and occipital lobes,named the Frontal-Parietal-Occipital bundles(FPOB).The fibers left mean fibers were 126 bundles,right fibers were 133 bundles(t= -0.791, P0.05).Mean FA left was 0.369,the right was 0.370(t= -0.178,P0.05),difference between both sides was statistically insignificant(P0.05).But the individual difference was significant.Some of them were the left larger than the right side.The frontal parts kept in touch with the Broca area of the left posterior of inferior frontal gyre.Conclusions There is individual difference both sides of association fascicules. There may be a new fiber bundle in the hemisphere,and associate with frontal lobe,temporal lobe,parietal lobe and occipital lobe.