Abstract
Hexahydroquinolines 1a, 1b reacted with carbon disulphide in different conditions to yield the corresponding adducts 2a, 2b and 3a, 3b. Carrying out the same reactions in acetone as solvent produced the modified new products 4a, 4b. The interaction of pyrazolopyridine derivatives 5a, 5b, 5c, 5d with carbon disulphide under the same previous conditions furnished the isolated products 6a, 6b, 6c, 6d, 7a, 7b, 7c, 7d, and 8a, 8b, 8c, 8d. Studying the behavior of 1a, 1b or 5a, 5b, 5c, 5d toward Lawesson's reagent (LR) formed the final adducts 11a, 11b or 12a, 12b, 12c, 12d. The structure of synthesized compounds was confirmed with the spectroscopic and microanalytical data. The biological activities of 2a, 4a, 4b, 7a, 7c, 8d, 11a, 11b, 12b, and 12c were tested for antimicrobial evaluation.
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