Abstract

Though many experiments have shown central (hypothalamo-pituitary) regulation of corpus luteum function evidence exists to show that the uterus also plays an important role in this ovarian process. The broad areas reviewed here include effects hysterectomy effects of IUDs effects of conceptus effects of pathological changes of uterus and physiological mechanisms. Observations suggest that the transformation of functional corpora lutea into corpora albicans depends upon uterine stimulation. A luteolytic factor carried vascularly and/or local nervous connections may be important in this regard.

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