Abstract
Abstract PRP (Platelet-Rich Plasma) has been widely used to treat dermatological diseases, one of which is vitiligo. There have been a number of published trials evaluating PRP combined therapy for vitiligo. However, evidence-based knowledge is insufficient for making sound decisions. This systematic review conducted to assess the evidence of therapeutic effect of PRP for vitiligo as an adjuvant therapy. All data sources were identified through electronic database searches on PubMed, Cochrane Library and Google Schoolar to find randomized controlled trials (RCT). The result of this review descriptively present with table. This study identified 13 studies that met inclusion criteria. Eight studies show the significant therapeutic effect of PRP for vitiligo. The combination therapy with PRP resulted in a significantly greater clinical improvement in re-pigmentation compared to monotherapy. PRP demonstrates efficacy and safety, making it a viable therapeutic option as an adjuvant or alternative treatment for vitiligo, owing to its healing and regenerative attributes.
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