Abstract
The use of Doppler ultrasound evaluation to measure the peak systolic velocity of the fetal middle cerebral artery (MCA) has been a major breakthrough in the noninvasive detection of fetal anemia. An elevated peak MCA velocity of >1.5 multiples of the median is useful in the timing of the initial intrauterine transfusion (IUT) in the red cell-alloimmunized pregnancies. Data reported to date suggest that a threshold of 1.32 multiples of the median can be used to time the second IUT; the MCA Doppler evaluation does not appear sensitive for the timing of subsequent IUTs in these pregnancies. The peak MCA velocity has also proved useful in the detection of other anemic states that include Kell alloimmunization, fetal parvovirus infection, fetomaternal hemorrhage, alphathalassemia, and after-laser therapy for twin-twin transfusion.
Highlights
Цель исследования: усовершенствовать диагностику гемолитической болезни плода
A study group consisted of 42 pregnant women whose newborn infants had varying degrees of hemolytic disease
The women were divided into 3 subgroups according to the severity of neonatal hemolytic disease: 1) pregnant women whose neonates were born with severe hemolytic disease (n = 14); 2) those who gave birth to babies with moderate hemolytic disease (n = 11); 3) those who delivered infants with mild hemolytic disease (n = 17)
Summary
ПЕРИНАТОЛОГИЯ И НЕОНАТОЛОГИЯ снизили последний показатель до 10% [5, 6], однако методы требуют дальнейшего изучения и совершенствования. Основной неинвазивный метод диагностики гемолитической болезни плода – ультразвуковое исследование с доплерометрией пиковой систолической скорости кровотока в средней мозговой артерии плода [7,8,9,10]. Метод доплерометрии пиковой систолической скорости кровотока в средней мозговой артерии плода основан на том, что при увеличении степени тяжести гемолитической болезни скорость кровотока в средней мозговой артерии выше, чем у плода того же срока гестации, и степень изменения скорости кровотока обратно коррелирует с уровнем гематокрита [12,13,14]. Что увеличение скорости кровотока в средней мозговой артерии более 1,5 МоМ для данного срока гестации свидетельствует о средней либо тяжелой степени анемии у плода.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
