Abstract
Currently, much attention is being paid to the status of vitamin D as a biomarker of the general state of human health, since low levels of vitamin D are associated with a wide range of diseases. Vitamin D metabolism is complex. Vitamin D and its containers can have genomic and non-genomic activity. The article presents the most common causes of vitamin D deficiency. Screening for vitamin D deficiency is shown in groups of patients with risk factors for its development. Individual features of vitamin D influence caused by genetic polymorphism of the VDR gene are described. For the prevention and treatment of vitamin D-deficient conditions, the use of the vitamin D preparation colecalciferol is recommended. Drugs with high activity calcitriol and alfacalcidol are necessary in certain groups of patients for strict indications, in particular in the complex therapy of osteoporosis.
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