The use of ultrasound in the recovery of biological particles

Abstract

Many of the physical effects of ultrasound have been known and exploited for some time. In the area of biotechnology, however, its use has been limited to small scale cell disruption and sensing. The authors examine a novel use of ultrasonic standing waves for the selective manipulation of shear sensitive biological particles with diameters in the range of one micrometer. Key uses in the field of biochemical engineering are described along with details of novel techniques developed to measure scale-up parameters. >