Abstract
The use of sildenafil in severe early-onset fetal growth restriction: a case report and review of current literature
Highlights
Early-onset severe fetal growth restriction (FGR) is diagnosed when the estimated fetal weight or abdominal circumference is less than the 3rd percentile before 32 weeks gestation; a condition which complicates 0.2-0.4% of all pregnancies [1,2,3]
A 38-year-old G4P2102 at 20 0/7 weeks’ gestation presented to our institution for a detailed fetal anatomic examination ultrasound. Her past obstetrical history was significant for an uncomplicated fullterm delivery followed by a 26-week stillbirth in a pregnancy affected by severe FGR and severe preeclampsia
Sildenafil acts as a vasodilator by inhibiting the enzyme cyclic GMP phosphodiesterase type 5 and prolongs nitric oxide's effect
Summary
The use of sildenafil in severe early-onset fetal growth restriction: A case report and review of current literature.
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