Abstract

To determine whether rocuronium would provide safe, short-term immobilization in Podocnemis expansa. Twenty P. expansa, weighing on average 1.59 +/- 0.28 kg, were subjected to two protocols: G1 0.25 mg/kg IM of rocuronium and 0.07 mg/kg IM of neostigmine, while G2 received 0.50 mg/kg IM of rocuronium and 0.07 mg/kg IM of neostigmine. The drugs were applied, respectively, in the left and right thoracic members. Assessments were made of the anesthetic parameters of respiratory frequency, heartbeat, righting reflex, cloacal relaxation, palpebral and pupilar reflexes, easy handling, muscle relaxation, locomotion, response to pain stimuli in the right thoracic members, pelvic members and tail, ambient humidity and temperature. They were not found statistical differences between the dosages for the majority of the assessments. G1 was as efficient as G2. A consistent neuromuscular blockade effect was recorded 12 +/- 4.21 minutes in G1 and G2. All the animals were recovered in 150 minutes. Administration of rocuronium at dose of 0.25 to 0.5 mg/kg IM is a safe and effective adjunct to clinical proceedings or pre-anesthetics in P. expansa. Because rocuronium does not provide any analgesic or sedative effects, the duration of neuromuscular blockade without anesthesia should be minimized to avoid undue stress.

Highlights

  • Amazon river turtle is distributed in the Amazon river basin, which encompasses equatorial forest and savannah ecosystems in the northern and mid-western regions of Brazil[13]

  • The purpose of this paper is to describe the results and side effects of pharmacological containment with neuromuscular rocuronium in doses of 0.25 mg/kg IM and 0.50 mg/kg IM in P. expansa

  • Rocuronium was administered in the muscle of the left thoracic member, and five min after the effect of muscle relaxation 3 and handling 3 took hold, neostigmine was applied in the muscle of the right thoracic member, using 25 x 0.70 mm hypodermic needles with syringes

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Summary

Introduction

Amazon river turtle is distributed in the Amazon river basin, which encompasses equatorial forest and savannah ecosystems in the northern and mid-western regions of Brazil[13]. CITESa and IUCNb today classify this animal as conservation dependent to not being under threat of extinction. In the eminence a Convenrion on International Trade in Endangered Species of Wild Fauna and Flora b International Union for Conservation of Natures and Natural Resources of the illegal threat with the capture of the animals in its habitats, there were published the IBAMAc Order no. 142/92, to govern the commercial breeding and legal consumption of terrapins provided from captivity. Pharmacological restraint of turtles for routine physical examination and diagnostic or therapeutic procedures is often required in zoological institutions, exotic animal breeding and wildlife and exotic animal practices. Its marked characteristic is the faster onset of its action in mammals than that provided by other commercially available relaxants, without causing the release of histamine or any major cardiovascular effect. Decurarization, consists of the phase in which the intention is to increase the concentration of acetylcholine (ACh) in the motor endplate by administering an anticholinesterase inhibitor such as neostigmine

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