Abstract
Regenerative endodontic procedures (REPs) are a biologically based treatment approach for immature permanent teeth that have been diagnosed with pulp necrosis. The primary objective of REPs is to regenerate the pulp-dentin complex, thereby increasing the tooth's lifespan and restoring its normal function. The success of REPs depends on several factors, including patient age, apical opening size, root development stage, and the presence of infection. Biomaterials used in REPs have also been shown to influence clinical outcomes. Several challenges and limitations still need to be addressed to improve the clinical outcomes of REPs, including disinfection of the root canal, selection of biomaterials, and availability of stem cells. Future research should focus on developing novel disinfection strategies, identifying the ideal biomaterials for REPs, and exploring alternative sources of stem cells. With continued research and development, REPs have the potential to become a viable alternative to traditional endodontic procedures for treating immature teeth with open apices.
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