Abstract

LEFT VENTRICULAR ASSIST DEVICES (LVADs) are becoming more prevalent in the treatment of heart failure. Nonpulsatile LVADs require long-term anticoagulation to prevent device thrombosis. Life-threatening bleeding or the need for urgent noncardiac surgery may necessitate reversal of this anticoagulation. The authors describe 2 cases of successful reversal of oral anticoagulation with prothrombin complex concentrates (PCCs) in patients with LVADs undergoing urgent noncardiac surgery, without evidence of device thrombosis.

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