Abstract

The laryngopharyngeal reflex (LPR) is associated with many diseases of the ear, nose, and throat. LPR is characterized by a retrograde flow of gastric contents into the larynx and pharynx, which leads to a recurrent course of otolaryngological symptoms. Proton pump inhibitors (PPIs) are currently the gold standard for LPR. However, there is increasing evidence that not all patients respond satisfactorily to PPIs. 30-35% of patients with LPR require additional intervention to control the symptoms of the disease. Oral probiotics show promise in the treatment of LPR, but evidence is still lacking. Further research is needed to evaluate the impact of oral probiotics on oral, pharyngeal, and laryngeal health.

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