Abstract
Objectives: The aim of the present study was to evaluate the use of platelet rich fibrin and Nano-hydroxyapatite as a regenerative treatment in furcation class II defect. Material and methods: Eight young adult dogs was selected for the study; in each dog, class II furcation defects were surgically created in 4 premolars and were treated as follow: First was treated with Nano hydroxyapatite alone ; Second with PRF alone ; Third with Nano hydroxyapatite and PRF ; Fourth did not receive any additional treatment than debridement (controls). Results: histomorphometric analysis revealed that, the greatest amount of newly formed bone was observed in the (PRF+ NHA bone) group, followed by the PRF group, then the NHA group, with the least recorded in the control group. The difference was not statistically significant except in comparing (PRF+ NHA group) with control group (p=0.0035). Conclusion: The combined use of both PRF and Nano hydroxyapatite in treatment of furcation class II defects could accelerate healing processes, getting use of the synergic effect of the powerful inherent regenerative potential of PRF and Nano hydroxyapatite.
Highlights
Periodontitis is one of the most common diseases affecting the periodontium
Heinz et al,. 2010 reported that nanocrystalline hydroxyapatite bone graft substitute in treatment of intrabony periodontal defects, showed more reduction in the probing pocket depth (PPD) in the study group compared with the control group
Analysis of variance (ANOVA) test revealed that the difference was statistically significant (p
Summary
Periodontitis is one of the most common diseases affecting the periodontium. Its main cause is bacterial plaque, that can result in destruction of the gingival tissues and10.21608/adjc.2020.19236.1035 periodontal supporting apparatus (Wang et al, 2005). Periodontitis is one of the most common diseases affecting the periodontium. Its main cause is bacterial plaque, that can result in destruction of the gingival tissues and. Hydroxyapatites (HAs) is considered as a family of grafting materials that have a high level of biocompatibility. It has decreased osteoconductivity and poor degradation properties. To improve such shortcomings, nanocrystalline hydroxyapatite (nano-HA) paste containing 65% water and 35% of nanostructured apatite particles has been used for augmentation procedures in intrabony defects (Thorwarth et al, 2005)
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