Abstract
Abstract With oxidised cellulose as a carboxylic cation exchange medium strychnine can be separated from extraneous interfering materials in a pure form for spectrophotometric assay. When brucine is also present a 2-point spectrophotometric procedure is adopted. Results compare well with chemical assays with a coefficient of variation of about 1 per cent. The oxidation procedure used in the official assay of nux vomica completely destroys brucine with no loss of strychnine.
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