Abstract
The aim of the study was to explore the effect of Thiocetam (combination of pyracetam and thiotriazoline) on recovery of neurological functions, social adaptation and improvement of the mental and emotional states of patients with ischemic stroke. Patients and methods: The study involved 250 patients (132 females and 118 males) aged 38 to 85 years (mean age 68.3 years) after an ischemic stroke. All patients received treatment aimed at preventing recurrent stroke (antithrombotic and antihypertensive drugs, statins) and restoring the lost functions (therapeutic exercise, etc.). Additionally, 125 patients received intravenous infusion of Thiocetam at a dose of 30 ml for 14 days, then 1 tablet TID for 1 month (group 1); the second group included 125 patients who received no Thiocetam (control group). Results: Thiocetam facilitated recovery of neurological functions and social adaptation, normalized the emotional state of patients after a stroke. Further randomized, placebo-controlled studies of Thiocetam efficacy in patients with ischemic stroke are required.
Highlights
Цель исследования – изучение влияния тиоцетама на восстановление неврологических функций, социально-бытовой адаптации и улучшение психоэмоционального состояния у пациентов, перенесших ишемический инсульт
The aim of the study was to explore the effect of Thiocetam on recovery of neurological functions, social adaptation and improvement of the mental and emotional states of patients with ischemic stroke
All patients received treatment aimed at preventing recurrent stroke and restoring the lost functions
Summary
Цель исследования – изучение влияния тиоцетама (комбинация пирацетама и тиотриазолина) на восстановление неврологических функций, социально-бытовой адаптации и улучшение психоэмоционального состояния у пациентов, перенесших ишемический инсульт. Направленное на профилактику повторного инсульта (антитромботические и антигипертензивные препараты, статины) и восстановление утраченных функций (лечебная гимнастика и др.). Что тиоцетам способствовал восстановлению неврологических функций, социально-бытовой адаптации, нормализации эмоционального состояния у пациентов после инсульта. The use of neurocytoprotectors to improve rehabilitation of patients after cerebrovascular accident Kovalchuk V.V. N.A. Semashko City Hospital No 38, St. Petersburg, Russia Gospital'naya Str., 5/7, Pushkin, St. Petersburg, 196601, Russia. The aim of the study was to explore the effect of Thiocetam (combination of pyracetam and thiotriazoline) on recovery of neurological functions, social adaptation and improvement of the mental and emotional states of patients with ischemic stroke
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