Abstract

Increased multiplication rates were observed in asexual erythrocytic stages of Plasmodium falciparum grown in the presence of a feeder-cell layer of mouse peritoneal wash cells (PWCs) using the candle-jar method of Trager and Jensen (1977). This held true for both new and established isolates of the parasite. When the PWC population was separated into adherent and non-adherent fractions, the adherent PWC population promoted an increase in parasite growth but the non-adherent population did not. An increase in parasite multiplication was not promoted by PWC-conditioned medium.

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