Abstract
Malignant melanoma (MM) is an aggressive heterogeneous skin cancer with phenotypic, immunoprofile, and molecular diversity. Some tumors may be undifferentiated, with loss of immunohistochemical markers and a less differentiated lesion status. These authors explored the immunoprofile and genetic landscape of 14 metastatic undifferentiated melanomas. These melanomas were more frequent in males (median age, 67 years), one with an unknown primary. …
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