Abstract
Calculations have been performed on series of pteridines and triazines using CNDO/2 and empirical steric methods, in an attempt to explain the variation of the enzyme inhibitory potency with structure. Potencies of inhibition of dihydrofolate reductase from several sources are considered. The variation in the relationships obtained according to enzyme source and substrate series are rationalize
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.