Abstract
The article presents an analysis of the work carried out on the basis of dairy farms in the Smolensk region for the period from 2008 to 2022. The application of new antimastitis drugs annually was carried out in order to prevent the formation of resistant strains of microorganisms, the main causative agents of mastitis and the selection of modern medicines for highly effective therapy of breast disease, as well as to create stable immunity and general resistance of the organism of lactating cows. Over the years of research, the high therapeutic efficacy of medicinal products was observed in the range of 82.3 - 98.2% and was evaluated in three days of treatment of cows with mastitis. Among the medicines used, the most effective were colimast and multiject 98.2% (2017), primalact 96.7% (2020), mastinone 95.0% (2019). When the were used, the signs of the inflammatory process of the mammary gland disappeared gradually, but by the 3rd day of treatment, milk secretion was completely restored and the condition of the animal as a whole improved significantly.
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