Abstract

Abstract Microcrystal tests have long been used for the rapid identification of particulate matter, although this technique has now been largely abandoned in favor of sophisticated instrumentation. The sensitivity and specificity of a microcrystal test make it an attractive method for the initial screening of powders for drugs of abuse. By combining the techniques of crystal microscopy and micro-FTIR, both preliminary and confirmatory tests for the presence of drugs in solid dosage forms are able to be carried out. This techniques has been used to unequivocally identify cocaine, heroin, morphine, codeine, and phencyclidine.

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