Abstract
A 6-year-old male patient underwent a liver transplant a year ago because of fulminant hepatitis and was treated with tacrolimus and prednisolone. The patient was evaluated because of reports of oral lesions, pain, and fever. An erythematous mucosa was observed in the upper and lower lip and soft palate. The diagnostic hypothesis was tacrolimus-induced mucosal toxicity. The case was discussed with the medical team, which replaced tacrolimus with sirolimus. We opted for the application of low-level laser therapy daily as an adjuvant treatment in addition to diet and hygiene recommendations. Patient reported 80% improvement and presented less erythematous oral mucosa, cessation of fever, improved oral acceptance of the diet, and reduction of painful symptoms after 3 days. Thus, the performance of an interdisciplinary team in complex clinical cases is essential for the success of the treatment, improvement of the patient's quality of life, and reduction of injuries resulting from the pharmacological therapy instituted.
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