Abstract

The need of hemostatic gauze to be used where packing is now necessary in deep seated operations, such as perineal prostatectomies, in which bleeding occurs within the prostatic capsule from which large hypertrophied lobes have been enucleated, has long been recognized at this clinic. This hidden intracapsular bleeding is often considerable, and many strips of iodoform gauze tightly packed within the prostatic capsule have often been necessary, and are even then not entirely successful. Accordingly I have experimented with a gauze impregnated with kephalin, which was shown by Prof. William H. Howell to be the best clot forming substance. Following his methods I have made kephalin from the brains of hogs.1 The gauze is prepared as follows: The kephalin is dissolved in an excess of ether, about a 5 per cent. solution being made, and this concentrated kephalin solution is poured over gauze strips 6 feet long and 6

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