Abstract

The aim of review is to show the benefits of plant species Carapichea ipecacuanha, its unique emetic properties and various compounds. C. ipecacuanha is a plant native to South and Central American rainforests. Its root contains two powerful alkaloids, emetine and cephaeline, which have emetic and expectorant properties. These roots are used to make ipecac syrup, which is used in both human and veterinary medicine. The most important use of ipecac syrup is vomiting induction, after the toxic compounds ingestion or after a drug overdose. In low doses, it serves as an expectorant to thin mucus and relieve coughing. Chemical compounds, such as emetine and cephaeline extracted from the plant have multiple functions in treating various ailments. Thus, it is important to get familiar with this plant species from a medicinal perspective.

Highlights

  • Numerous effects of plants, both medicinal and toxic, have been established throughout history

  • In the 19th century, it was discovered that the root of ipecac contained two active substances, emetine and cephaeline, which were responsible for the induction of vomiting and diarrhea (Lee, 2008)

  • The aim of this review is to show the benefits of plant species Carapichea ipecacuanha, its unique emetic properties and various compounds

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Summary

Introduction

Both medicinal and toxic, have been established throughout history. In the 19th century, it was discovered that the root of ipecac contained two active substances, emetine and cephaeline, which were responsible for the induction of vomiting and diarrhea (Lee, 2008). Ipecac root (Ipecacuanhae radix) contains several alkaloids which are pharmaceutically used against respiratory diseases such as bronchitis accompanied with cough in children, severe diarrhea ( known as amoebic dysentery) and malignant diseases (Gorunović and Lukić, 2001; Petrović, 2002).

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