Abstract
A new method that involves the use of ion-exchange resins to study ion transport in biological systems is presented. The transport of organic and inorganic ions was studied in a variety of biological systems including intact cells, sub-cellular particles (Such as mitochondria and plasma membrane vesicles), and reconstituted membrane vesicles. A comparison with such conventional methods as centrifugation and washing, gel filtration, and membrane filtration suggests that the method has certain advantages with respect to reproducibility, reliability, and convenience.
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