Abstract
Background: Constipation is a common disorder in children.Objective: The objective of this study is to assess the beneficial effects of a daily supplementation with Orafti® inulin‐type fructans in 2–5 year old constipated children.Methods: Double‐blind, randomised, placebo‐controlled parallel group trial where constipated children received two doses of 2 g Orafti® inulin‐type fructans (OF:IN) or placebo (maltodextrin) for 6 weeks. Primary outcome was stool consistency. Secondary outcomes were stool frequency and gastrointestinal symptoms.Results: Twenty-two children were included, 17 completed the study protocol (nine and eight for the control and the OF:IN group, respectively). Results showed that Orafti® inulin‐type fructans supplemented children had softer stools (p = .003). The longitudinal analysis showed no significant changes in controls, whereas supplemented children increased their stool consistency from 2.2 to 2.6 on the modified Bristol scale for children (five items instead of seven) (p = .040).Conclusions: Prebiotic inulin‐type fructans supplementation improves stool consistency in constipated 2–5-year old children.Clinicaltrials.gov, with number NCT02863848.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Food Sciences and Nutrition
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
