Abstract

A new sulfonamide drug with an effective diuretic property - hypothiazide (hydrochlorothiazide, hydrodiuryl, dichlotride), (6 chloro-7-sulfanyl-1, 2, 4-benzodihydrothiadiazine - 1,1-dioxide) was synthesized simultaneously, but independently, Stevens and Koenig in 1958.

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