Abstract

BackgroundFunctional neurological disorder is defined by symptoms not explained by the current model of disease and its pathophysiology. It is found in 8.4% of patients presenting as acute stroke. Treatment is difficult and recurrence rates are high. We introduced hypnotherapy as a therapeutic option in addition to standard stroke unit care.MethodsThis is an observational study of successive patients with functional neurological disorder presenting as acute stroke treated with hypnotherapy between 1 April 2014 and 1 February 2018. The diagnosis of functional neurological disorder was confirmed by clinical examination and computed tomography/magnetic resonance imaging. Hypnosis was delivered by a hypnotherapy trained stroke physician using imagery for induction. A positive response was defined as a National Institutes of Health Stroke score reduction to 0 or by ≥4 points posthypnotherapy. Costs were calculated as therapist time and benefits as reduction in disability/bed days.ResultsSixty-eight patients (mean age 36.4 years, 52 (76%) females, mean baseline National Institutes of Health Stroke 5.0 (range 1–9)) were included. Two patients (3%) could not be hypnotized. Fifty-eight 58 (85%) responded, 47 (81%) required one treatment session, while 19% needed up to three sessions for symptomatic improvement. No adverse events were observed. Disability (modified Rankin Scale) reduced from a mean of 2.3 to 0.5 resulting in an average cost saving of £1,658 per patient. Most (n = 50, 86%) remained well without recurrence at six-month follow-up.ConclusionsIn this case series, hypnotherapy was associated with rapid and sustained recovery of symptoms. A prospective randomized controlled study is required to confirm the findings and establish generalizability of the results.

Highlights

  • Functional neurological disorder (FND) is a term used to describe a condition where the symptoms are not explained by the current disease model and its pathophysiology

  • Studies from the UK and continental Europe established that one third of the new patients seen in neurology clinics have symptoms that are only partially explained by organic disease.[1,2,3,4]

  • We introduced hypnotherapy as an additional treatment option for patients presenting with functional symptoms[11] mimicking acute stroke

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Summary

Introduction

Functional neurological disorder (FND) is a term used to describe a condition where the symptoms are not explained by the current disease model and its pathophysiology. NHS Scotland recommends a stepped care model starting with diagnosis and explanation, followed by brief interventions such as cognitive behavior therapy and self-help, where needed, and a multidisciplinary approach for refractory cases.[5] A recent review. Functional neurological disorder is defined by symptoms not explained by the current model of disease and its pathophysiology. It is found in 8.4% of patients presenting as acute stroke. Treatment is difficult and recurrence rates are high. We introduced hypnotherapy as a therapeutic option in addition to standard stroke unit care

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