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Abstract
Characterization of cell populations through measuring cell diameters proves to be an adequate method in following processes of change in cell populations. Several distinct sorts of cells with volumes related in a ratio of about 1:2:4 can be present in cell populations. In the degenerative phase of cell strains of human skin fibroblasts this ratio is disturbed and the frequency distributions become more polymodal. The analysed permanent cell lines of human origin showed the same volume classes as normal cells did. Their nuclear disturbances were not reflected in the cell diameters in a perceptible way.
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