Abstract

The use of centrally acting drugs in behavior therapy is reviewed. The use of such compounds in aversion procedures has been largely superseded by other techniques and their main indication in behavior therapy is in the treatment of phobic symptoms. The psychophysiological rationale underlying this use of pharmacological agents is discussed with particular reference to the concept of arousal. Two types of preparation are considered in some detail: (1) drugs administered orally to reduce “free-floating” anxiety—these include hypnosedatives, plus major and minor tranquillizers (anxiolytics); (2) intravenous agents used in subanesthetic doses to produce relaxation during specific desensitization procedures—these include methohexital sodium (Brevital, Brietal) and propanidid (Epontol). It is concluded that the intravenous preparations in particular can be of considerable value when used as adjuncts to the behavior therapy of phobic symptoms and other situational anxieties.

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