Abstract
The present article will provide an overview of use of dried blood sampling method for analysis of drug of abuse. Relatively short half life and instability in blood, calls for alternative sampling method for determination of drugs of abuse. Dried blood spot (DBS) method has many advantages over the conventional sampling methods. The available method for DBS sample collection, storage and transport are described here. The techniques involved in and the factors that may influence the accuracy and reproducibility of the DBS methods for determination of drugs of abuse are presented. The DBS sampling has the potential to be a useful technique to detect drugs of abuse. The use of DBS for any drug should be judged against the potential error involved with the method.
Highlights
Screening of various body fluids to detect presence of drugs of abuse is a very useful technique in clinical, forensic and research contexts
The use of Dried blood spot (DBS) for any drug should be judged against the potential error involved with the method
For the sake of clarity of understanding the review has been organized in the following headings: Dried Blood Spot: Sample Collection, Storage & Transport and Review of Drugs of Abuse Assays with the DBS Method
Summary
Screening of various body fluids to detect presence of drugs of abuse is a very useful technique in clinical, forensic and research contexts. To reduce the time of sample collection and analysis in a stable matrix and to reduce the handling of infectious diseases the use of dried blood spot (DBS) could be an alternative [5,6]. Use of dried blood spots may circumvents various issues like short half life of drugs in blood, time lapse between blood collection and drug analysis, risk of infection and monitoring of therapeutic drugs from a remote place. In this regard it was found worthwhile to provide an overview of the use of dried blood spots in screening drugs of abuse in the literature. For the sake of clarity of understanding the review has been organized in the following headings: Dried Blood Spot: Sample Collection, Storage & Transport and Review of Drugs of Abuse Assays with the DBS Method
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
