The use of cysteine to normalize interoceptive reflexes altered by the action of toxic substances of ascarides

Abstract

In acute experiments on cats under urethane anesthesia the author studied the change of the vascular and respiratory reflexes from the chemoceptors of a humorally isolated intestine following the action of ascarides toxic substances (Ascarissuum water extracts or the metabolites of these parasites produced in vitro), as well as the normalizing effect of cysteine. As established, the vascular and respiratory reflexes, altered as a result of the toxic products of ascarides, become normalized after the administration of cysteine. In the presence of marked ascariasis in cats, the interoceptive reflexes from the chemoceptors of the isolated intestine are similarly changed; cysteine administration also normalizes the reflexes in natural Ascaris infestation.