Abstract
To evaluate the effect of clomiphene citrates (CC) on inducing ovulation and on cyst persistence and size in women with functional ovarian cysts. Randomized controlled trial. University Maternity Hospital. 60 women in 2 equal groups. Clomiphene citrates treatment, follicle scanning, hormonal assay. Ovulation rate, pregnancy rate, cyst persistence, changes in cyst size. CC increased both ovulation and pregnancy rates in women with functional ovarian cysts (56.7% versus 13.3%, p < 0.000 for ovulation and 23.0% versus 6.7%, p < 0.000 for pregnancy). CC also increased cyst persistence rate especially in cases achieving pregnancy (30% versus 6.7%, p < 0.000) but did not increase the size of the cyst, or cause complications in it. Clomiphene citrates significantly increased ovulation, pregnancy and cyst persistence rates in women with functional ovarian cysts.
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