Abstract

Brain natriuretic peptide (BNP) is one member of natriuretic peptide family and mainly secreted by ventricular myocardium. BNP has many functions such as natriuresis, diuresis, dilation of blood vessels, inhibition of renin-angiotensin-aldosterone system and sympathetic nervous system activity. In recent years, BNP analysis widely used in fields of adult diseases, especially in cardiovascular disease. But research and application of BNP in pediatrics diseases is still relatively small. This article reviewed biology character and the progress of BNP in pediatric diseases. Key words: Brain natriuretic peptide; Children; Diseases

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